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Pharmacy One
Travel vaccine

Dengue vaccination

This vaccine is only suitable for people who have previously had a confirmed dengue infection. It is not recommended for those with no prior exposure.

Dengue fever is a viral infection spread by daytime-biting Aedes mosquitoes in tropical and subtropical regions worldwide. It causes a range of symptoms from a mild fever to severe joint and muscle pain, and a small proportion of cases develop into a life-threatening form known as severe dengue. There is no specific antiviral treatment, making prevention through mosquito bite avoidance and, where eligible, vaccination the key approach.

A vaccine for dengue is now available in the UK (Qdenga). However, its use is carefully restricted: it is licensed for adults aged 18 to 60 who can confirm they have previously had dengue, based on a positive blood test or clinical diagnosis. Administering the vaccine to someone with no prior dengue infection is not recommended, as it may paradoxically increase the risk of severe disease on a subsequent natural infection.

If you have had dengue before and are travelling frequently to endemic regions, speak to our pharmacist to find out whether you are a suitable candidate. Because the course requires three doses spread over 12 months, it is a longer term commitment. Call us on 0161 437 2634 for a travel consultation to discuss your individual eligibility.

When you need this vaccine

  • Adults aged 18 to 60 with laboratory-confirmed previous dengue infection travelling to dengue-endemic areas
  • Travel to tropical and subtropical regions of South and South-East Asia, Central and South America, the Caribbean, and parts of Africa
  • Frequent travellers to endemic destinations who have documented prior dengue exposure
  • Not recommended for people with no prior dengue infection, as the vaccine may increase risk of severe dengue in seronegative individuals

Schedule

  1. Three doses given by subcutaneous injection at 0, 6, and 12 months.
  2. All three doses are needed to complete the course and achieve the best protection.
  3. The vaccine (Qdenga) requires seropositive status to be confirmed before administration.
  4. Plan at least 12 months ahead if the full 3-dose course is needed before a future trip.

Frequently asked questions

Can I have the dengue vaccine if I have never had dengue before?
No. The currently licensed dengue vaccine is only recommended for people with documented prior dengue infection. Using it in people without prior exposure may increase the risk of severe illness if they are later infected.
Are there side effects?
The most common reactions include pain and redness at the injection site, headache, and mild flu-like symptoms. Serious side effects are uncommon but should be discussed at your appointment.
Does the vaccine cover all dengue virus types?
Qdenga provides protection against all four dengue serotypes, though efficacy varies. Your pharmacist can discuss the expected level of protection based on available clinical evidence.